This verse establishes the role of God as Creator. The universe was not created by mindless matter but rather by an intelligent Creator. It implies a distinction between things that come into existence and the One who has always existed. In other words, there is one thing that did not come into existence: God.
Here, we see that the eternal God, who existed before creation began, demonstrated His almighty power through the incarnate Word. As the perfect Son of Man, Jesus Christ, our Lord, was clothed in flesh at an appointed time in order to save fallen humanity from eternal punishment for sin. Humanity was restored to a proper relationship with God through His salvation.
All things were created by Christ Jesus, the almighty Creator. However, our limited mortal minds are unable to comprehend many of the marvelous mysteries of godliness. Therefore, He revealed what we need to know through His eternal Word. He was also made flesh and dwelt among us so that by grace through faith, we could be made righteous by simply believing in Him and residing with Him for all eternity.

Dear Heavenly Father, our eternal Creator, You are worthy of all honor, glory, and praise for in Christ Jesus we have become a new creation. Thank You that the Word became flesh and dwelt among mankind. Besides creating us through Him, you saved us with a price, through the blood of Jesus Christ, so that we may be made the righteousness of God in Him and bear witness in the events of our lives to come before you no longer do so.
In Jesus's name I pray. Amen.